[1P-099] Identification of Plasmodium falciparum mitochondrial malate:quinone oxidoreductase and dihydroorotate dehydrogenase inhibitors as antimalarial drug candidate

^○Hartuti Endah D¹, Sakura Takaya^2,3, Wang Xinying³, Mochizuki Kota¹, Archarjee Rajib¹, Matsuo Yuichi⁴, Nozaki Tomoyoshi⁵, Hamano Shinjiro⁶, Kita Kiyoshi^3,4,5, K Inaoka Daniel^2,3,5 (1.Grad School of Biomedical Science, Nagasaki University, 2.Dept of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 3.School of Tropical Medicine and Global Health, Nagasaki University, 4.Dept of Host-Defense Biochemistry, NEKKEN, Nagasaki University, 5.Dept of Biomedical Chemistry, Grad School of Medicine, The University of Tokyo, 6.Dept of Parasitology, NEKKEN, Nagasaki University)

キーテクノロジー：inhibitor screening

Plasmodium falciparum、mitochondrial ETC、MQO、DHODH、HTS