The effect of MO2455 and its derivatives, a novel compound that induces the accumulation of poly (ADP-ribose), on cancer cells

Yuka Sasaki

[1P-265] The effect of MO2455 and its derivatives, a novel compound that induces the accumulation of poly (ADP-ribose), on cancer cells

^○Yuka Sasaki^1,2, Takae Onodera^1,2, Kenji Matsuno³, Takeji Takamura⁴, Kengo Inoue⁵, Tatsu Shimoyama⁶, Fumiaki Koizumi^1,6, Mitsuko Masutani^1,2,6 (1.Dept. Frontier Life Sci., Grad. Sch. Biomed. Sci., Nagasaki Univ., 2.Lab. Collaborative Res., Div. Cellular Signaling, Natl. Cancer Ctr. Res. Inst., 3.Faculty of Engineering, Kogakuin Univ., 4.Faculty of Engineering, Kanagawa Inst. of Tech., 5.Pharma Valley Center, 6.Div. Clin. Res. Support, Komagome Hosp.)

キーテクノロジー：PDXモデル

PARG、ポリ（ＡＤＰ-リボース）、抗がん剤

yukasasa@nagasaki-u.ac.jp

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The 92nd Annual Meeting of JBS

[1P-265] The effect of MO2455 and its derivatives, a novel compound that induces the accumulation of poly (ADP-ribose), on cancer cells

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