The Japanese Biochemical Society

[1P-265] The effect of MO2455 and its derivatives, a novel compound that induces the accumulation of poly (ADP-ribose), on cancer cells

Yuka Sasaki1,2, Takae Onodera1,2, Kenji Matsuno3, Takeji Takamura4, Kengo Inoue5, Tatsu Shimoyama6, Fumiaki Koizumi1,6, Mitsuko Masutani1,2,6 (1.Dept. Frontier Life Sci., Grad. Sch. Biomed. Sci., Nagasaki Univ., 2.Lab. Collaborative Res., Div. Cellular Signaling, Natl. Cancer Ctr. Res. Inst., 3.Faculty of Engineering, Kogakuin Univ., 4.Faculty of Engineering, Kanagawa Inst. of Tech., 5.Pharma Valley Center, 6.Div. Clin. Res. Support, Komagome Hosp.)

キーテクノロジー:PDXモデル

PARG、ポリ(ADP-リボース)、抗がん剤

yukasasa@nagasaki-u.ac.jp

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