The Japanese Biochemical Society

[1P-269] Functional significance of mutant IDH1 and p16 in cartilage-forming tumors

Takeshi Kamakura1,2, Yonghui Jin1,3, Makoto Watanabe4, Takeshi Okamoto3,5, Hiroyuki Yoshitomi1,2,5, Junya Toguchida1,2,5 (1.Dept. Tissue Regeneration, Inst. for Front. Life and Med.Sci., Kyoto Univ., 2.Dept. Cell Growth and Differentiation, CiRA, Kyoto Univ., 3.Inst. for Advancement of a Clin. and Transl. Sci., Kyoto Univ. Hosp., Kyoto Univ., 4.Life Sci. Res. Ctr., Shimadzu Corporation, 5.Dept. Orthopaedic Surgery, Grad.Sch. Med., Kyoto Univ.)

キーテクノロジー:CRISPR/Cas9

IDH、p16、CRISPR/Cas9、MSC、iPS

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