The Japanese Biochemical Society

[1P-345] Generation and characterization of antagonistic anti-human interleukin (IL)-18 monoclonal antibodies with high affinity

Yuko Nariai1, Hiroki Kamino1, Eiji Obayashi1, Kiyoshi Migita2, Atsushi Kawakami3, Kouhei Tsumoto4,5, Takeshi Urano1 (1.Department of Biochemistry, Shimane University School of Medicine, 2.Department of Rheumatology, Fukushima Medical University School of Medicine, 3.Department of Rheumatology, Unit of Advanced Preventive Medical Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 4.Department of Bioengineering, School of Engineering, The University of Tokyo, 5.Institute of Medical Science, The University of Tokyo)

キーテクノロジー:capillary Western immunoassay

monoclonal antibody、interleukin-18 (IL-18)、antagonistic antibody、neoepitope

nariai@med.shimane-u.ac.jp

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