Anticancer Sulfonamides Target DCAF15-DDB1-CUL4 Ubiquitin Ligase to Promote Selective Degradation of Splicing Factor RBM39

Taisuke Uehara

10:00 AM - 10:20 AM

[1S03m-04] Anticancer Sulfonamides Target DCAF15-DDB1-CUL4 Ubiquitin Ligase to Promote Selective Degradation of Splicing Factor RBM39

^○Taisuke Uehara¹, Yukinori Minoshima¹, Koji Sagane¹, Naoko Sugi¹, Kaoru Mitsuhashi¹, Noboru Yamamoto¹, Hiroshi Kamiyama¹, Kentaro Takahashi¹, Yoshihiko Kotake¹, Mai Uesugi¹, Akira Yokoi¹, atsushi Inoue¹, Miyuki Mabuchi², Akito Tanaka², Takashi Owa¹ (1.Eisai Co., Ltd., 2.School of pharmacy, Hyogo University of Health Sciences)

キーテクノロジー：プロテオミクス

プロテオミクス、ユビキチン、タンパク質分解、抗がん剤

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The 92nd Annual Meeting of JBS

[1S03m-04] Anticancer Sulfonamides Target DCAF15-DDB1-CUL4 Ubiquitin Ligase to Promote Selective Degradation of Splicing Factor RBM39

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