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[1T06a-03] Identification of Plasmodium falciparum mitochondrial malate:quinone oxidoreductase and dihydroorotate dehydrogenase inhibitors as antimalarial drug candidate

Hartuti Endah D1, Sakura Takaya2,3, Wang Xinying3, Mochizuki Kota1, Archarjee Rajib1, Matsuo Yuichi4, Nozaki Tomoyoshi5, Hamano Shinjiro6, Kita Kiyoshi3,4,5, K Inaoka Daniel2,3,5 (1.Grad School of Biomedical Science, Nagasaki University, 2.Dept of Molecular Infection Dynamics, Institute of Tropical Medicine (NEKKEN), Nagasaki University, 3.School of Tropical Medicine and Global Health, Nagasaki University, 4.Dept of Host-Defense Biochemistry, NEKKEN, Nagasaki University, 5.Dept of Biomedical Chemistry, Grad School of Medicine, The University of Tokyo, 6.Dept of Parasitology, NEKKEN, Nagasaki University)

キーテクノロジー:inhibitor screening

Plasmodium falciparum、mitochondrial ETC、MQO、DHODH、HTS

endah.dwi08@yahoo.co.id

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