The Japanese Biochemical Society

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[1T14a-01] Deletion of class II ARFs in mice causes tremor by inhibiting Nav1.6 localization to cerebellar Purkinje cell axon initial segments.

Tetsushi Sadakata1, Nobutake Hosoi2, Koji Shibasaki3, Ayumu Konno2, Hirokazu Hirai2, Yasuki Ishizaki3, Teiichi Furuichi4 (1.Education and Research Support Center, Gunma University Graduate School of Medicine, 2.Department of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, 3.Department of Molecular and Cellular Neurobiology, Gunma University Graduate School of Medicine, 4.Department of Applied Biological Science, Tokyo University of Science)

キーテクノロジー:遺伝子改変マウス

ARF、Nav1.6、AIS、trafficking

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