The Japanese Biochemical Society

The 92nd Annual Meeting of JBS

The 92nd Annual Meeting of JBS

Sep 18, 2019 - Sep 20, 2019
Pacifico Yokohama

11:30 AM - 11:40 AM

[1T14m-03] Antigen recognition mechanism of an affinity-matured single chain Fv antibody against anti-(4-hydroxy-3-nitrophenyl)acetyl

○Akihiro Nishiguchi1, Nobutaka Numoto2, Nobutoshi Ito2, Takachika Azuma3, Masayuki Oda1 (1.Grad. Sch. Life Environ. Sci., Kyoto Pref. Univ., 2.Med. Res. Inst., Tokyo Med. Dent. Univ., 3.Antibody Eng. Res. Center)

キーテクノロジー：X-ray crystallography

scFv、affinity maturation、somatic hyper mutation、H-CDR3、antigen-binding

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