[2P-066] In silico design of PD-1 mutation to inhibit PD-1/PD-L1 immune checkpoint pathway

^○Ning Boyang^1,2, Hideyuki Miyatake^1,2, Yoshihiro Ito^1,3 (1.Nano Medical Engineering Laboratory, RIKEN Cluster for Pioneering Research, 2.Department of Life Science, Graduate School of Science and Engineering, Saitama University, 3.Emergent Bioengineering Materials Research Team, RIKEN Center for Emergent Matter Science)

キーテクノロジー：in-silico protein engineering

Immune check point inhibitor、PD-1/PD-L1、In silico selection、Protein complimentary assay、Protein engineering