[2P-088] The N-terminal sequence of murine PRMT5 variant 2 is required for interaction with Hsp70 and CHIP ligase-mediated degradation

^○Weizhe Lu¹, Jun-dal Kim², Saori Tabara³, Chulwon Kwon³, Akiyoshi Fukamizu^1,2 (1.Ph.D. Program in Human Biology, School of Integrative Global Majors (SIGMA), University of Tsukuba, 2.Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, 3.Graduate School of Life and Environmental Sciences, University of Tsukuba)

キーテクノロジー：Western Blotting

PRMT5、Splice variants、NH2-terminus、Hsp70/CHIP、Protein degradation