The Japanese Biochemical Society

[2P-183] Identification of a chemical chaperone targeting protein aggregation under ER stress

Keisuke Kitakaze1,2, Shusuke Taniuchi1, Eri Kawano1, Yoshimasa Hamada1, Masato Miyake1, Miho Oyadomari1, Hirotatsu Kojima3, Hidetaka Kosako4, Tomoko Kuribara5, Suguru Yoshida5, Takamitsu Hosoya5, Seiichi Oyadomari1 (1.Div. of Mol. Biol., Inst. of Adv. Med. Sci., Tokushima Univ., 2.Dept. of Pharmacol., Kawasaki Med. Sch., 3.DDI, The Univ. of Tokyo, 4.Fujii Memorial Inst. of Med. Sci., Inst. of Adv. Med. Sci., Tokushima Univ., 5.Lab. of Chem. Biosci., Inst. of Biomater. and Bioeng., TMDU)

キーテクノロジー:レポーター遺伝子

小胞体ストレス、UPR、シャペロン、化合物スクリーニング

kitakaze@med.kawasaki-m.ac.jp

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