The Japanese Biochemical Society

[2P-224] Lysine demethylase 7a regulates anterior-posterior development via modulating Hox gene cluster transcription in mice

Yoshiki Higashijima1,6, Nao Nagai2, Taro Kitazawa3,5, Yumiko Kawamura3,5, Masaomi Nangaku4, Hiroki Kurihara5, Youichiro Wada6, Tetsushi Furukawa1, Yasuharu Kanki6 (1.Department of Bioinformational Pharmacology, Tokyo Medical and Dental University, 2.Department of Microbiology and Immunology, Keio University School of Medicine, 3.Friedrich Miescher Institute for Biomedical Research, 4.Division of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine, 5.Department of Physiological Chemistry and Metabolism, The University of Tokyo Graduate School of Medicine, 6.Isotope Science Center, The University of Tokyo)

キーテクノロジー:ChIP-seq, RNA-seq, CRISPR/Cas9

エピジェネティクス、ヒストン修飾酵素、H3K9me2、Hox遺伝子群、前後軸形成

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