[2P-224] Lysine demethylase 7a regulates anterior-posterior development via modulating Hox gene cluster transcription in mice

^○Yoshiki Higashijima^1,6, Nao Nagai², Taro Kitazawa^3,5, Yumiko Kawamura^3,5, Masaomi Nangaku⁴, Hiroki Kurihara⁵, Youichiro Wada⁶, Tetsushi Furukawa¹, Yasuharu Kanki⁶ (1.Department of Bioinformational Pharmacology, Tokyo Medical and Dental University, 2.Department of Microbiology and Immunology, Keio University School of Medicine, 3.Friedrich Miescher Institute for Biomedical Research, 4.Division of Nephrology and Endocrinology, The University of Tokyo Graduate School of Medicine, 5.Department of Physiological Chemistry and Metabolism, The University of Tokyo Graduate School of Medicine, 6.Isotope Science Center, The University of Tokyo)

キーテクノロジー：ChIP-seq, RNA-seq, CRISPR/Cas9

エピジェネティクス、ヒストン修飾酵素、H3K9me2、Hox遺伝子群、前後軸形成