3:30 PM - 3:50 PM

[2S11a-04] Sphingosine 1-phosphate-dependent switching of endothelial transcription factors in angiogenesis and endothelial specialization

^○Keisuke Yanagida^1,2, Eric Engelbrecht², Colin Niaudet², Konstantin Gaengel³, Kristina Holton⁴, Steven Swendeman², Catherine H. Liu⁵, Michel V. Levesque², Andrew Kuo², Zhongjie Fu⁶, Lois E. H. Smith⁶, Christer Betsholtz^3,7, Timothy Hla² (1.Department of Lipid Signaling, National Center for Global Health and Medicine, 2.Vascular Biology Program, Boston Children's Hospital, Harvard Medical School, 3.Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, 4.Harvard Medical School Research Computing, 5.Department of Medicine, Weill Cornell Medicine, 6.Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, 7.ICMC (Integrated Cardio Metabolic Centre), Karolinska Institutet)

キーテクノロジー：ATAC-seq

スフィンゴシン1リン酸、血管新生、血管成熟、Gタンパク質共役型受容体、ATAC-seq