The Japanese Biochemical Society

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[2T05m-04] PARP1 inhibitors alleviate injury in ARH3-deficient mice and human cells

Kazumasa Aoyama1, Masato Mashimo1, Xiangning Bu1, Jiro Kato1, Hiroko Ishiwata-Endo1, Linda A Stevens1, Atsushi Kasamatsu1, Lynne A Wolfe2, Camilo Toro2, David Adams2,3, Thomas Markello2, William A Gahl2,3, Joel Moss1 (1.Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health (NIH), 2.NIH Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health (NIH), 3.Office of the Clinical Director, National Human Genome Research Institute, National Institutes of Health (NIH))

キーテクノロジー:DNA sequence

ARH3、Poly(ADP-ribosyl)ation、Parthanatos

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