The Japanese Biochemical Society

The 92nd Annual Meeting of JBS

The 92nd Annual Meeting of JBS

Sep 18, 2019 - Sep 20, 2019
Pacifico Yokohama

2:10 PM - 2:20 PM

[2T06a-06] A novel mechanism of Rac1 activation as a therapeutic target for HER2-positive breast cancers

○Masashi Maekawa1,2, Akari Murakami2,3, Katsuhisa Kawai4, Jun Nakayama5, Nobukazu Araki4, Kentaro Semba5, Tomohiko Taguchi6, Yoshiaki Kamei3, Yasutsugu Takada3, Shigeki Higashiyama1,2 (1.Division of Cell Growth and Tumor Regulation, Proteo-Science Center, Ehime University, 2.Department of Biochemistry and Molecular Genetics, Ehime University Graduate School of Medicine, 3.Department of Hepato-Biliary-Pancreatic Surgery and Breast Surgery, Ehime University Graduate School of Medicine, 4.Department of Histology and Cell Biology, School of Medicine, Kagawa University, 5.Department of Life Science and Medical Bioscience, School of Advanced Science and Engineering, Waseda University, 6.Department of Integrative Life Sciences, Graduate School of Life Sciences, Tohoku University)

キーテクノロジー：生細胞観察

Cullin-3 (CUL3)、Rac1、Membrane ruffle、HER2陽性乳癌、RhoB

mmaekawa0924@gmail.com

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