The Japanese Biochemical Society

11:20 AM - 11:30 AM

[2T17m-02] Galectin 3 binding protein suppresses Aβ production via modulation of endogenous β-secretase activity

Tsuneyoshi Seki1, Motoi Kanagawa1, Kazuhiro Kobayashi1, Hisatomo Kowa2, Naoki Yahata3,6, Kei Maruyama4, Nobuhisa Iwata5, Haruhisa Inoue6,7,8, Tatsushi Toda1,9 (1.Division of Neurology/Molecular Brain Science, Kobe University Graduate School of Medicine, 2.Department of Rehabilitation Science, Kobe University Graduate School of Health Sciences, 3.Department of Anatomy I, Fujita Health University School of Medicine, 4.Department of Pharmacology, Faculty of Medicine, Saitama Medical University, 5.Department of Genome- based Drug Discovery, Graduate School of Biomedical Sciences, Nagasaki University, 6.Center for iPS Cell Research and Application (CiRA), 7.iPSC-based Drug Discovery and Development Team, RIKEN BioResource Research Center (BRC), 8.Medical-risk Avoidance based on iPS Cells Team, RIKEN Center for Advanced Intelligence Project (AIP), 9.Department of Neurology, Graduate School of Medicine, The University of Tokyo)

キーテクノロジー:iPS細胞

Alzheimer’s disease、iPS細胞、GAL3BP、BACE1、microarray

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