The Japanese Biochemical Society

[3P-266] Novel degradation mechanism of BRCA1 following mitochondrial damage in breast cancer cells.

Naoharu Takano1, Kana Miyahara2, Yumiko Yamada1, Hiromi Kazama1, Mayumi Tokuhisa1, Hirotsugu Hino1, Koji Fujita3, Edward Barroga4, Masaki Hiramoto1, Hiroshi Handa5, Masahiko Kuroda3, Takashi Ishikawa2, Keisuke Miyazawa1 (1.Dept. of Biochem., Tokyo Med. Univ., 2.Dept of Breast Oncology and Surgery, Tokyo Med. Univ., 3.Dept. of Mol. Path., Tokyo Med. Univ., 4.Dept. of Med. Education, Tokyo Med. Univ., 5.Dept. of Nanoparticle Translational Res., Tokyo Med. Univ.)

キーテクノロジー:ウェスタンブロット

BRCA1、PINK1、Parkin、ミトコンドリア

ntakano@tokyo-med.ac.jp

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