[3P-266] Novel degradation mechanism of BRCA1 following mitochondrial damage in breast cancer cells.

^○Naoharu Takano¹, Kana Miyahara², Yumiko Yamada¹, Hiromi Kazama¹, Mayumi Tokuhisa¹, Hirotsugu Hino¹, Koji Fujita³, Edward Barroga⁴, Masaki Hiramoto¹, Hiroshi Handa⁵, Masahiko Kuroda³, Takashi Ishikawa², Keisuke Miyazawa¹ (1.Dept. of Biochem., Tokyo Med. Univ., 2.Dept of Breast Oncology and Surgery, Tokyo Med. Univ., 3.Dept. of Mol. Path., Tokyo Med. Univ., 4.Dept. of Med. Education, Tokyo Med. Univ., 5.Dept. of Nanoparticle Translational Res., Tokyo Med. Univ.)

キーテクノロジー：ウェスタンブロット

BRCA1、PINK1、Parkin、ミトコンドリア