The Japanese Biochemical Society

[3P-274] Suppression of intestinal tumorigenicity in mice lacking TMEPAI gene involved in a negative feedback loop of TGF-β signaling

Risako Azuma1, Teppei Shibasaki1, Keigo Sano1, Shouei Amano1, Yutaro Sawada1, Ryo Ishikawa1, Fumiko Itoh2, Yukihide Watanabe3, Makoto M. Taketo4, Mitsuyasu Kato3, Susumu Itoh1 (1.Laboratory of Biochemistry, Showa Pharmaceutical University, 2.Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, 3.Laboratory of Experimental Phathology, University of Tsukuba, 4.Division of Experimental Therapeutics Graduate School of Medicine Kyoto University)

キーテクノロジー:ノックアウトマウス

TGF-β、TMEPAI、Apc

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