Blockade of IL-4Rα suppresses the development of fibrosis through attenuation of the HMGB1/α2AP axis in mouse models of systemic sclerosis

Yosuke Kanno

[3P-299] Blockade of IL-4Rα suppresses the development of fibrosis through attenuation of the HMGB1/α2AP axis in mouse models of systemic sclerosis

^○Yosuke Kanno^1,2, En Shu², Hirofumi Niwa², Hiroyuki Kanoh², Mariko Seishima² (1.Faculty of Pharmaceutical Science, Doshisha Womens College of Liberal Arts, 2.Department of Dermatology, Gifu University Graduate School of Medicine)

キーテクノロジー：病態モデルマウス

fibrosis、Systemic sclerosis、α2AP、HMGB1、IL-4α

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The 92nd Annual Meeting of JBS

[3P-299] Blockade of IL-4Rα suppresses the development of fibrosis through attenuation of the HMGB1/α2AP axis in mouse models of systemic sclerosis

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