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[3T11m-05] Depletion of axonal mitochondria disrupts protein degradation and induces accumulation of ubiquitinated proteins in the Drosophila brain

Kanako Shinno1, Mikiko Oka1, Emiko Suzuki2,3, Koichi M. Iijima4,5, Kanae Ando1 (1.Lab of Mol Neurosci, Dept of Bio Sci, Grad Sch of Sci, Tokyo Metropolitan Univ, 2.Gene Network Lab, National Inst of Genetics, 3.Dept of Genetics, Sch of Life Sci, SOKENDAI, 4.National Center for Geriatrics and Gerontology, Dept of Alzheimer's Disease Research, 5.Grad Sch of Pharmaceutical Sci, Deprt of Experimental Gerontology, Nagoya City Univ)

キーテクノロジー:ショウジョウバエモデル

Mitochondria、axonal transport、autophagy、aging、Drosophila

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