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[3T18e-04] Cdk5 increases MARK4 activity and augments pathological tau accumulation and toxicity through tau phosphorylation at Ser262

Saito Taro1, Oba Toshiya1, Shimizu Sawako1, Akiko Asada1, Koichi M. Iijima2,3, Ando Kanae1 (1.Dept Biol Sci, Tokyo Met Univ, Tokyo, Japan, 2.Dept Alzheimer's Dis Res, NCGG, Aichi, Japan, 3.Dept Exp Gerontology, Grad Sch Pharm Sci, Nagoya City Univ, Aichi, Japan)

キーテクノロジー:Drosophila model

tau、Cdk5、MARK

tasaito@tmu.ac.jp

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