[2P-292] The control of osteoclast differentiation by oxidation of intracellular proteins.

^○Keita Taniguchi¹, Tsukasa Tominari¹, Ryota Ichimaru², Chiho Matsumoto¹, Michiko Hirata¹, Chisato Miyaura^1,2, Masaki Inada^1,2 (1.Department of Biotechnology and Life Science, Tokyo Univ. of Agri. and Tech., 2.Cooperative Major of Advanced Health Science, Tokyo Univ. of Agri. and Tech.)

The 92nd Annual Meeting of JBS

[2P-293] Effect of substrate stiffness on osteoclast differentiation

^○Katsuhiro Abe¹, Tsukasa Tominari¹, Ryouta Ichimaru², Chiho Matsumoto¹, Michiko Hirata¹, Chisato Miyaura^1,2, Masaki Inada^1,2 (1.Dept. of Biotech. And Life Sci., Tokyo Univ. of Agri. And Tech., 2.Cooperative Major of Advanced Health Science, Tokyo Univ. of Agri. And Tech.)

The 92nd Annual Meeting of JBS

[2P-294] Elucidation of PMO uptake mechanism via Caveolin 3 in dystrophin-deficient muscle cell membrane

^○Taisuke Ohno^1,3, Hotake Takizawa³, Yoshitaka Mizobe³, Yuko Hara³, Tsoumpra Maria³, Yasumasa Hashimoto³, Nordin Joel³, Yuichiro Tone³, Ryota Ichimaru², Tsukasa Tominari¹, Michiko Hirata¹, Masaki Inada^1,2, Chisato Miyaura^1,2 (1.Dept. of Biotech. And Life Sci., Tokyo Univ. of Agri. and Tech., 2.Dept. of Graduate school of Bio-Applications And Systems Engineering., Tokyo Univ. of Agri. and Tech., 3.Department of Molecular Therapy, National Institute of Neuroscience, National Center for Neurology and Psychiatry.)

The 92nd Annual Meeting of JBS

[2P-295] Heme deficiency causes insulin resistance due to impaired glycogen synthesis induced by reducing AMP-activated kinase signals

Shinichi Saitoh^1,2, Koen van Wijk¹, Tomohiro Kimura¹, Tsukasa Osaki³, Satoshi Okano¹, Masayuki Yamamoto⁴, Hironobu Asao², Kelly Vincent P.⁵, Kiwamu Takahashi⁶, Tohru Tanaka⁶, Motowo Nakajima⁶, ^○Osamu Nakajima¹ (1.Yamagata University School of Medicine, Research Center for Molecular Genetics, 2.Department of Immunology, Yamagata University School of Medicine, 3.Department of Public Health, Yamagata University School of Medicine, 4.Department of Medical Biochemistry, Tohoku University School of Medicine,, 5.Trinity Biomedical Sciences Institute, Trinity College Dublin, 6.SBI Pharmaceuticals Co.,Ltd.)

The 92nd Annual Meeting of JBS

[2P-296] The role of tissue-specific splicing variants of the type 2 ryanodine receptor in pancreatic β cells

^○Mai Makino¹, Asako Itaya-Hironaka¹, Akiyo Yamauchi¹, Sumiyo Sakuramoto-Tsuchida¹, Tomoko Uchiyama^1,2, Ryogo Shobatake^1,3, Shin Takasawa¹ (1.Department of Biochemistry, Nara Medical University, 2.Department of Diagnostic Pathology, Nara Medical University, 3.Department of Neurology, Nara Medical University)

The 92nd Annual Meeting of JBS

[2P-297] Crosstalk between neutrophils and adipocytes initiates adipose tissue inflammation

^○Yasuharu Watanabe¹, Yoshinori Nagai², Kiyoshi Takatsu¹ (1.The Toyama Prefectural Institute for Pharmaceutical Research, 2.Department of Pharmaceutical Engineering, Faculty of Engineering, Toyama Prefectural University)

The 92nd Annual Meeting of JBS

[2P-298] CDH13 Polymorphisms are associated with adiponectin levels and metabolic syndrome traits independently of visceral fat mass.

^○Aya Kitamoto¹, Takuya Kitamoto¹, Chiharu Uchida¹, Kikuko Hotta² (1.Advanced Research Facilities and Services, Hamamatsu University School of Medicine, 2.Department of Pharmacy, Osaka Ohtani University)

The 92nd Annual Meeting of JBS

[2P-299] Transcriptional and translational regulation on fetal growth restriction in Pregnancy-associated hypertensive mice

^○Junji Ishida¹, Jun-Dal Kim¹, Siquan Huo², Misaki Nakashima², Akiyoshi Fukamizu¹ (1.Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance, University of Tsukuba, 2.Agro-biological Resource Sciences, Graduate School of Life and Environmental Sciences, University of Tsukuba)

The 92nd Annual Meeting of JBS

[2P-300] Protein analysis of infertile male testis by two-dimensional electrophoresis-relationship between Johnsen's score & protein spots-

^○Haruka Yoshizawa¹, Ryoei Hara², Saori Kitazawa^3,4, Shin Ohira², Seitetsu Sugiyama², Atsushi Nagai², Shigenobu Tone¹ (1.Graduate School of Science and Engineering,Tokyo Denki University, 2.Department of Urology,Kawasaki Medical School, 3.School of Science and Engineering,Tokyo Denki University, 4.Showa Kouyu Co., Ltd.)

The 92nd Annual Meeting of JBS

[2P-301] Down-regulation of miR-484 expression was caused expression of PCDH19, resulting in reduce the risk of PCDH19 related syndorome.

^○Kana Sato, Katsuya Iuchi, Hisashi Hisatomi (Laboratory of Cellular and Molecular Biochemistry, Department of Materials and Life Science, Seikei University)

The 92nd Annual Meeting of JBS