[3P-280] A short-chain fatty acid, propionate, enhances the cytotoxic effect of cisplatin by modulating GPR41/FFA3 signaling pathways in HepG2 cells

^○Mamiko Kobayashi¹, Daisuke Mikami¹, Junsuke Uwada², Takashi Yazawa², Yudai Nishikawa¹, Takanobu Taniguchi², Masayuki Iwano¹ (1.Department of Nephrology, Faculty of Medical Sciences, University of Fukui, 2.Division of Cellular Siganl Transduction, Department of Biochemistry, Asahikawa Medical University)

The 92nd Annual Meeting of JBS

[3P-281] Investigation on growth retardation and sensitivity to carcinogen in aldehyde reductase (Ak1a)-knockout mice

^○Naoki Ishii, Takujiro Homma, Junichi Fujii (Graduate School of Medical Science, Yamagata University)

The 92nd Annual Meeting of JBS

[3P-282] Identification of 16 modifier loci post-K-ras mutation by QTL analysis using K-rasG12V mediated lung tumor mouse models.

^○Hiromitsu Saito, Noboru Suzuki (Department of Animal Functional Genomics of Advanced Science Research Promotion Center,Organization for the Promotion of Regional Innovation)

The 92nd Annual Meeting of JBS

[3P-283] NASH-like finding in Q137E RP S19 knock-in male mice

^○HIROSHI NISHIURA, KOUJI YAMANEGI (Pathology, Hyogo Collage of Medicine)

The 92nd Annual Meeting of JBS

[3P-284] Mechanism of anti-obesity effect by ChREBP inhibition

^○Haruhiko Sakiyama¹, Lan Li¹, Tsutomu Nakagawa², Hironobu Eguchi¹, Daisaku Yoshihara¹, Noriko Fujiwara¹, Keiichiro Suzuki¹ (1.Hyogo college of medicine Department of Biochemistry, 2.Health Sciences University of Hokkaido Faculty of Pharmacetical Sciences)

The 92nd Annual Meeting of JBS

[3P-285] Regulation of fructose-induced fatty liver by nonessential amino acid

^○Makoto Shimizu¹, Ayumi Funo², Yoshio Yamauchi^1,2, Ryuichiro Sato^1,2 (1.Nutri-Life Science Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 2.Food Biochemistry Laboratory, Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo)

The 92nd Annual Meeting of JBS

[3P-286] Protective effect of black carrot extract on alcoholic liver disease and its mechanism

^○Atsuko Kitano¹, Toshio Norikura², Hiromi Shimakawa³, Makoto Kamezawa³, Isao Matsui-Yuasa¹, Akiko Kojima-Yuasa¹ (1.Graduate School of Human Life Science, Osaka City University, 2.Aomori University of health and Welfare, 3.Konan Chemical Industry, Co. LTD.)

The 92nd Annual Meeting of JBS

[3P-287] Therapeutic effect of lysophosphatidylcholine acyltransferase overexpression in the liver for diabetes mellitus in a mouse model

^○Kahori Shimizu¹, Moe Ono¹, Takenari Mikamoto¹, Yuya Urayama¹, Hiroki Nakanishi², Tomoyuki Terada¹, Fuminori Sakurai³, Hiroyuki Mizuguchi^3,4,5, Koji Tomita¹, Toru Nishinaka¹ (1.Pharma., Osaka Ohtani Univ., 2.Research Center for Biosignal, Akita Univ., 3.Grad. Sch. of Pharma. Sci., Osaka Univ., 4.Natl. Inst. of Biomed. Innov. Health Nutr., 5.MEIC, Osaka Univ)

The 92nd Annual Meeting of JBS

[3P-288] Effect of LL-37, a human antimicrobial peptide, on autophagy and cell death of endothelial cells

^○Kaori Suzuki, Mari Ohkuma, Isao Nagaoka (Dept. Host Defense and Biochemical Research, Juntendo Univ. Sch. Med.)

The 92nd Annual Meeting of JBS

[3P-289] The effect of glucose concentration in culture medium on phosphorylation of histone H2AX induced by ultraviolet irradiation

^○Saki Ono, Yukako Komaki, Yuko Ibuki (Department of Environmental and Life Sciences, School of Food and Nutritional Sciences, University of Shizuoka)

The 92nd Annual Meeting of JBS