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[1Z05-03(P-209)] Structural and catalytic properties of P219L human D-amino acid oxidase: implications for the ligand binding and catalytic efficiency

Wanitcha Rachadech1,2, Yusuke Kato1, Rabab M. Abou El-Magd1,4, Yuji Shishido1, Soo Hyeon Kim1, Hirofumi Sogabe1, Nobuo Maita3, Kazuko Yorita1, Fukui Kiyoshi1 (1.Div. of Enzyme Pathophysiol., Inst. for Enzyme Res., Tokushima Univ., Japan, 2.Div. of Chemistry, Faculty of Science, Udon Thani Rajabhat Univ., Thailand, 3.Div. of Disease Proteomics, Inst. for Enzyme Res., Tokushima Univ., Japan, 4.Depart. of Psychiatry, Faculty of Medicine, Univ. of Alberta, Canada)

キーテクノロジー:X-ray crystallography

human D-amino acid oxidase、active site lid、point-mutation

c201756011@tokushima-u.ac.jp

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