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[2Z11-08(P-434)] Development of a NanoBiT-based conformational sensor reveals structural differences among ligand/GPCR-dependent β-arrestin conformations.

Misaki Yoshida1, Kouki Kawakami1, Suzune Hiratsuka1, Arun K. Shukla2, Junken Aoki3,4, Asuka Inoue1,4 (1.Dept. of Mol. Cell. Biochem., Grad. Sch. of Pharm. Sci., Tohoku Univ., 2.Indian Institute of Technology, Kanpur, 3.Dept. of Health Chem., Grad. Sch. of Pharm. Sci., Univ. of Tokyo, 4.LEAP, AMED)

キーテクノロジー:細胞アッセイ

Gタンパク質共役型受容体、βアレスチン、NanoBiTシステム、IB30

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