The Japanese Biochemical Society

The 93rd Annual Meeting of JBS

The 93rd Annual Meeting of JBS

Sep 14, 2020 - Sep 16, 2020
Web

[P-027(2Z01-01)] EDEM2 stably disulfide bonded to TXNDC11 initiates mannose trimming in mammalian glycoprotein ER-associated degradation

○Satoshi Ninagawa1, Ginto George1, Hirokazu Yagi2, Yoshiki Sumitomo1, Tokiro Ishikawa1, Tetsushi Sakuma3, Takashi Yamamoto3, Koshi Imami4, Yasushi Ishihama4, Koichi Kato2,5, Tetsuya Okada1, Kazutoshi Mori1 (1.Department of Biophysics, Graduate School of Science, Kyoto University, 2.Graduate School of Pharmaceutical Sciences, Nagoya City University, 3.Division of Integrated Sciences for Life, Graduate School of Integrated Sciences for Life, Hiroshima University, 4.Department of Molecular and Cellular BioAnalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 5.Exploratory Research Center on Life and Living Systems (ExCELLS) and Institute for Molecular Science, National Institutes of Natural Sciences)

キーテクノロジー：タンパク精製

小胞体関連分解、糖鎖、マンノース、EDEM、ジスルフィド結合

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