A missense mutation at Leu74Pro of OGR1 found in familial amelogenesis imperfecta is actually lost in the pH-sensing mechanism

Koichi Sato

[P-393] A missense mutation at Leu74Pro of OGR1 found in familial amelogenesis imperfecta is actually lost in the pH-sensing mechanism

^○Koichi Sato¹, Chihiro Mogi¹, Alan J. Mighell², Fumikazu Okajima³ (1.IMCR, Gunma Univ., 2.Sch. of Dent., Univ. of Leeds, 3.Fac. of Pharm. Sci., Aomori Univ.)

キーテクノロジー：細胞応答

extracellular acidification、G protein-coupled receptor、intracellular Ca²⁺、missense variant、OGR1

kosato@gunma-u.ac.jp

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The 93rd Annual Meeting of JBS

[P-393] A missense mutation at Leu74Pro of OGR1 found in familial amelogenesis imperfecta is actually lost in the pH-sensing mechanism

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