[P-410] London dispersion force acting between bisphenol-halogen atoms and estrogen receptors causes a strong functional ERα-agonist / ERβ-antagonist activities

^○Xiaohui Liu^1,2, Keitaro Suyama^1,3, Junichi Shiki¹, Kohei Torikai¹, Takeru Nose^1,3, Miki Shimohigashi^4,5, Yasuyuki Shimohigashi^1,5 (1.Dept. of Chem., Fac. and Grad. Sch. of Sci., Kyushu Univ.,, 2.Dept. of Appl. Microb. Tech., Fac. of Biotech. and life Sci., Sojo Univ.,, 3.Fac. of Arts and Sci., Kyushu Univ.,, 4.Lab. of Biol., Fac. of Sci., Fukuoka Univ.,, 5.Risk Sci. Res. Ins.)

キーテクノロジー：ハロゲン含有化合物の受容体活性

ハロゲン含有ビスフェノール、エストロゲン受容体、二価性活性、London分散力、核内受容体