The Japanese Biochemical Society

[P-422] Molecular Mechanisms of G-protein dependent β-arrestin biased agonism in Angiotensin2(AT1) receptor.

Kouki Kawakami1, Masataka Yanagawa2, Suzune hiratsuka1, Arun K. Shukla3, Yasushi Sako2, Junken Aoki1,4,5, Asuka Inoue1,5,6 (1.Dept. of Mol. Cell. Biochem., Grad. Sch. of Pharm. Sci., Tohoku Univ., 2.Cellular Informatics Laboratory, RIKEN Cluster for Pioneering Research, 3.Indian Institute of Technology, Kanpur, 4.Dept. of Health Chem., Grad. Sch. of Pharm. Sci., Univ. of Tokyo, 5.LEAP, AMED, 6.PRIME, AMED)

キーテクノロジー:CRISPR, NanoBiT

GPCR、Gタンパク質、GRK、βアレスチン、シグナルバイアス

kouki.kawakami.p8@dc.tohoku.ac.jp

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