[P-453] SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations

^○Arato Takedachi^1,2,3, Despras Emmanuelle⁴, Sarah Scaglione², Raphael Guerois⁵, Jean-Hugues Guervilly², Marion Blin², Stephane Audebert², Luc Camoin², Zdenka Hasanova², Mike Schertzer^6,7, Arnaud Guille², Dmitri Churikov², Tomoki Nagasawa¹, Shoji Mizusaki¹, Isabelle Callebaut⁹, Valeria Naim¹⁰, Max Chaffanet², Jean-Paul Borg², Francois Bertucci², Isao Kuraoka¹, Patrick Revy⁸, Daniel Birnbaum², Arturo Londonno-Vallejo^6,7, Particia Kannouche⁴, Pierre-Henri Gaillard² (1.Department of Chemistry, Faculty of Science, Fukuoka University, 2.Centre de Recherche en Cancerologie de Marseille, CRCM, 3.Inovarion, 4.UMR 8200, Universite Paris Sud, Gustave Roussy, 5.Institute for Integrative Biology of the Cell, 6.Institut Curie, PSL Research University, CNRS, UMR3244, 7.Sorbonne Universites, UPMC Univ Paris 06, CNRS, UMR3244, 8.INSERM Unite UMR1163, Imagine Institute, 9.Sorbonne Universite, Museum National dHistoire Naturelle, UMR CNRS 7590, 10.UMR 8200, Universite Paris Sud, Gustave Roussy)

キーテクノロジー：DNA fiber assay

SLX4、RETL1、Hoyeraal-Hreidarsson症候群、がん、DNA複製