[P-464(1Z07-08)] SETDB1 represses H3K4/H3K9me3 bivalent genes by ubiquitination-dependent and -independent mechanisms

^○Ji Albert Zhang^1,4, Yoshihiro Matsumura¹, Yuka Kano¹, Ayano Yoshida¹, Takeshi Kawamura², Hiroyuki Hirakawa¹, Hiroyuki Aburatani³, Juro Sakai^1,4 (1.Division of Metabolic Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, 2.Proteomics Laboratory, Isotope Science Center, The University of Tokyo, Tokyo 113-0032, Japan, 3.Genome Science Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan, 4.Division of Molecular Physiology and Metabolism, Tohoku University Graduate School of Medicine)

キーテクノロジー：IP, LS/MS, ChIP-Seq

SETDB1、ubiquitination、adipogenesis、chromatin/ epigenetics