[P-485] Identification of kolaflavanone, a Garcinia biflavonoid, as novel inhibitor of mitotic kinesin Eg5

^○Tomisin H. Ogunwa¹, Kei Sadakane¹, Shinsaku Maruta¹, Takayuki Miyanishi², Olusola O. Elekofehinti³, Ayodele O. Kolawole³, Afolabi C. Akinmoladun³, Olaposi O. Omotuyi⁴ (1.Department of Bioinformatics, Graduate School of Engineering, Soka University, 1-236 Tangi-cho, Hachioji, Tokyo 192-8577, Japan, 2.Graduate School of Fisheries and Environmental Sciences, Nagasaki University, Nagasaki 852-8521, Japan, 3.Department of Biochemistry, The Federal University of Technology, Akure, Ondo State, Nigeria, 4.Department of Biochemistry, Adekunle Ajasin University, Akungba-Akoko, Ondo State, Nigeria)

キーテクノロジー：Kolaflavanone inhibited Eg5.

kinesin Eg5、kolaflavanone、biflavonoid、ATPase activity、molecular interaction