[P-580(1Z11-09)] Computational analysis of deamidation mechanisms of asparagine residues catalyzed by acetic acid

^○Tomoki Nakayoshi^1,2, Kota Wanita¹, Koichi Kato^1,3, Eiji Kurimoto¹, Akifumi Oda^1,2,4 (1.Graduate School of Pharmacy, Meijo University, 2.Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, 3.Department of Pharmacy, Kinjo Gakuin University, 4.Institute for Protein Research, Osaka University)

キーテクノロジー：量子化学計算

非酵素的反応、アスパラギン残基、脱アミド化、反応機構