[P-590] The regulation of pancreatic-α cell function by HNF-1α

^○Yoshifumi Sato¹, Rahman Md Mostafizur¹, Masaki Haneda¹, Tomoya Mizumoto¹, Tomonori Tsuyama², Tatsuya Yoshizawa¹, Tadahiro Kitamura³, J Gonzalez Frank⁴, Ken-ichi Yamamura⁵, Kazuya Yamagata^1,2 (1.Department of Medical Biochemistry, Faculty of Life Sciences, Kumamoto University, 2.Center for Metabolic Regulation of Healthy Aging, 3.Metabolic Signal Research Center, Institute for Molecular and Cellular Regulation, 4.Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States, 5.Institute of Resource Development and Analysis, Kumamoto University)

キーテクノロジー：ノックアウトマウス

グルカゴン、膵α細胞