The Japanese Biochemical Society

[P-592(3Z10-04)] Impaired glucose-stimulated insulin secretion in 5-aminolevulinate synthase 1 (ALAS1) gene knockout heterozygous mice

Kazuya Takeda1,2, Koen van Wijk1, Tomohiro Kimura1, Satoshi Okano1, Shinichi Saitho3, Hiroaki Yamaguchi2, Ken Kodama4, Kiwamu Takahashi5, Tohru Tanaka5, Motowo Nakajima5, Osamu Nakajima1 (1.Inst. for Promotion of Med.Sci. Res., Yamagata Univ. Sch. Med., 2.Dep. of Pharmacy, Yamagata Univ. Sch. Med., 3.Dep. of Immunol., Yamagata Univ. Sch. Med., 4.Neopharm Japan Co., Ltd., 5.SBI Pharmaceuticals Co., Ltd.)

キーテクノロジー:遺伝子破壊マウス

ヘム、5-アミノレブリン酸、糖尿病、グルコース刺激インスリン分泌、分離膵島

tkazuya@ameria.org

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