The Japanese Biochemical Society

[P-599] Haploinsufficiency of DGCR2 gene is implicated in the maxillofacial pathogenesis of 22q11.2 deletion syndrome

Kagemasa Kajiwara1, Go Nagashima2, Kyoka Tashiro2, Masahiro Uchibori3, Yoshihide Ohta3 (1.Tokai University, School of Medicine, Molecular Life Sciences, 2.Tokai University, School of Science, Division of Chemistry, 3.Tokai University, School of Medicine, Maxillofacial Surgery)

キーテクノロジー:Gene knockout/GFP knockin

DGCR2、22q11.2 deletion syndrome、ノックアウトマウス、頭蓋底軟骨結合、TGF-beta signal

kagemasa@is.icc.u-tokai.ac.jp

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