The Japanese Biochemical Society

[P-688] Identification of macrocyclic peptides that regulate the CD47-SIRPalpha system, and their potential as anti-cancer drugs

Yoji Murata1, Daisuke Hazama1, Yizhen Yin2, Makoto Matsuda3, Takeshi Okamoto1, Daisuke Tanaka1, Mariko Sakamoto1, Yuka Kakuchi1, Naohiro Terasaka2, Jinxuan Zhao2, Yasuyuki Saito1, Takenori Kotani1, Atsushi Nakagawa3, Hiroaki Suga2, Takashi Matozaki1 (1.Div. Mol & Cell. Signal., Dep. Biochem. & Mol. Biol., Kobe Univ. Grad. Sch. Med., 2.Lab. Bioorg. Chem., Grad. Sch. Sci., Univ. Tokyo, 3.Lab. Supramol. Crystallogr., Inst. Protein Res., Osaka Univ.)

キーテクノロジー:環状ペプチド

がん、環状ペプチド、貪食、マクロファージ、SIRPα

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