The Japanese Biochemical Society

[P-724(2Z10-12)] Effects of the ichthyosis-causative mutations in the ceramide synthase CERS3 on activity and stratum corneum ceramide composition

Moe Yamamoto1, Takayuki Sassa1,2, Yuki Kyouno3, Hiroyasu Uemura4, Masaaki Kugo4, Hideki Hayashi5, Yasutomo Imai5, Kiyofumi Yamanishi5, Akio Kihara1,2 (1.Grad. Sch. Life Sci., Hokkaido Univ., 2.Fac. Pharm. Sci., Hokkaido Univ., 3.Dept. Pediatrics, Kobe Univ., 4.Dept. Pediatrics, Japanese Red Cross Society Himeji Hosp., 5.Dept. Dermatol., Hyogo College of Med.)

キーテクノロジー:LC-MS/MS

セラミド、魚鱗癬、CERS3、アシルセラミド 、結合型セラミド

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