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[2Z12-08(P-763)] Single Enzyme Activity-based Protein Profiling - A Methodology for Ultra-sensitive Detection of Disease-related Alterations of Enzymatic Activities

Shingo Sakamoto1, Toru Komatsu1, Rikiya Watanabe2, Zhang Yi3, Taiki Inoue1, Mitsuyasu Kawaguchi4, Hidehiko Nakagawa4, Takaaki Ueno5, Takuji Okusaka6, Kazufumi Honda7, Hiroyuki Noji3,8, Yasuteru Urano1,9,10 (1.Grad. Sch. Pharm. Sci., The Univ. Tokyo, 2.RIKEN, 3.Grad. Sch. Eng., The Univ. Tokyo, 4.Grad. Sch. Pharm. Sci., Nagoya City Univ., 5.Osaka Dent. Univ., 6.Natl. Cancer Ctr. Hosp., 7.Natl. Cancer Ctr. Res. Inst., 8.ImPACT, 9.Grad. Sch. Med., The Univ. Tokyo, 10.AMED-CREST)

キーテクノロジー:ケミカルバイオロジー

1分子計測リキッドバイオプシー、酵素活性、タンパク質、1分子計測、マイクロデバイス

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