Single Enzyme Activity-based Protein Profiling - A Methodology for Ultra-sensitive Detection of Disease-related Alterations of Enzymatic Activities

Shingo Sakamoto

[P-763(2Z12-08)] Single Enzyme Activity-based Protein Profiling - A Methodology for Ultra-sensitive Detection of Disease-related Alterations of Enzymatic Activities

^○Shingo Sakamoto¹, Toru Komatsu¹, Rikiya Watanabe², Zhang Yi³, Taiki Inoue¹, Mitsuyasu Kawaguchi⁴, Hidehiko Nakagawa⁴, Takaaki Ueno⁵, Takuji Okusaka⁶, Kazufumi Honda⁷, Hiroyuki Noji^3,8, Yasuteru Urano^1,9,10 (1.Grad. Sch. Pharm. Sci., The Univ. Tokyo, 2.RIKEN, 3.Grad. Sch. Eng., The Univ. Tokyo, 4.Grad. Sch. Pharm. Sci., Nagoya City Univ., 5.Osaka Dent. Univ., 6.Natl. Cancer Ctr. Hosp., 7.Natl. Cancer Ctr. Res. Inst., 8.ImPACT, 9.Grad. Sch. Med., The Univ. Tokyo, 10.AMED-CREST)

キーテクノロジー：ケミカルバイオロジー

１分子計測リキッドバイオプシー、酵素活性、タンパク質、１分子計測、マイクロデバイス

tightend31@g.ecc.u-tokyo.ac.jp

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The 93rd Annual Meeting of JBS

[P-763(2Z12-08)] Single Enzyme Activity-based Protein Profiling - A Methodology for Ultra-sensitive Detection of Disease-related Alterations of Enzymatic Activities

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