The Japanese Biochemical Society

[P-774] Generation and characterization of single chain antibodies against occludin preventing hepatitis C virus infection.

Yoshimi Shimizu1,2, Takehiro Shinoda3, Yoshitaka Shirasago1, Masuo Kondoh4, Naoko Shinya3, Kentaro Hanada1, Kiyohito Yagi4, Tetsuro Suzuki5, Takaji Wakita6, Tomomi Someya3, Mikako Shirouzu3, Masayoshi Fukasawa1 (1.Department of Biochemistry and Cell Biology, National Institute of Infectious Diseases, 2.Department of Pharmaceutical Sciences, Teikyo Heisei University, 3.Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research, 4.Graduate School of Pharmaceutical Sciences, Osaka University, 5.Department of Infectious Diseases, Hamamatsu University School of Medicine, 6.Department of Virology II, National Institute of Infectious Disease)

キーテクノロジー:抗体改変技術

低分子抗体、Occludin、C型肝炎ウイルス、抗体

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