○Koen van Wijk1, Shinichi Saitoh1, Tomohiro Kimura1, Satoshi Okano1, Ken Kodama2, Kiwamu Takahashi3, Tohru Tanaka3, Motowo Nakajima3, Osamu Nakajima1(1.Yamagata University School of Medicine, 2.Neopharma Japan Co.,Ltd., 3.SBI Pharmaceuticals Co., Ltd.)