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[1T13m-07(P-019)] 3'-Sialyllactose on Notch: NOTCH1 functions as a scaffold of O-linked, 3'-sialyllactosylated glycans

Yohei Tsukamoto1, Kazuhiro Aoki2, Yoshiki Narimatsu3, Yusuke Urata1, Wataru Saiki1, Mitsutaka Ogawa1, Michael Tiemeyer2, Henrik Clausen3, Tetsuya Okajima1,4, Hideyuki Takeuchi1,4,5 (1.Department of Molecular Biochemistry, Nagoya University Graduate School of Medicine. Japan., 2.Complex Carbohydrate Research Center, University of Georgia. USA., 3.Department of Cellular and Molecular Medicine, University of Copenhagen. Denmark., 4.Institute for Glyco-Core Research (iGCORE), Nagoya University. Japan., 5.Department of Biochemistry University of Shizuoka School of Pharmaceutical Sciences)

キーテクノロジー:質量分析

O-グルコース糖鎖、シアリルラクトース、質量分析、Notchシグナル、EGFリピート

tsukamoto.yohei@j.mbox.nagoya-u.ac.jp

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