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[1T15e-01(P-946)] Novel aminocyclopropenone compound inhibits BRD4-driven NUP210 expression and attenuates cancer growth

Hiroya Kondo1, Kenji Mishiro2, Masaharu Hazawa2,3,4, Yuki Iwashima4, Akiko Kobayashi2, Kazuma Ogawa2, Wong Richard2,3,4 (1.Division of Transdisciplinary Sciences, Institute for Frontier Science Initiative, Kanazawa Univ., Japan, 2.Institute for Frontier Science Initiative, Kanazawa Univ., Japan, 3.WPI Nano Life Science Institute, Kanazawa univ., Japan, 4.Division of Life Science and Engineering, Institute for Science and Engineering, Kanazawa Univ., Japan)

キーテクノロジー:共焦点顕微鏡・WB法

BRD4、天然変性領域、相分離形成、核膜孔複合体、がん治療

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