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[1T15e-03(P-939)] A novel tetravalent peptide directly binds to APP to inhibit the production of Amyloid β in cells.

Waka Sato1, Miho Takahashi1, Hina Uchiyama2, Takashi Saito3, Takaomi Saido4, Satoru Funamoto2, Kiyotaka Nishikawa1 (1.Doshisha University, Grad. School of Life and Medical Sciences, Molecular Life Sciences, 2.Doshisha University, Grad. School of Life and Medical Sciences, Neuropathology, 3.Nagoya City University, Grad.School of Medical Science, Department of Neurocognitive Science, 4.Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science)

キーテクノロジー:多価型ペプチドライブラリー法

アルツハイマー病、APP、Amyloid β、β-セクレターゼ

cygd2005@mail4.doshisha.ac.jp

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