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[2T13a-08(P-483)] p300-mediated acetylation promotes MCL1 stabilization and tumorigenesis

Kouhei Shimizu1, Min Gi2,3, Shugo Suzuki2, Fuminori Tokunaga1, Hiroyuki Inuzuka4, Wenyi Wei4 (1.Department of Pathobiochemistry, Graduate School of Medicine, Osaka City University, 2.Department of Molecular Pathology, Graduate School of Medicine, Osaka City University, 3.Department of Environmental Risk Assessment, Graduate School of Medicine, Osaka City University, 4.Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School)

キーテクノロジー:anti-acetylated MCL1 antibody

Acetylation、Ubiquitination、Protein degradation、Apoptosis、MCL1

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