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[2T13a-11(P-488)] INSIGs mediate the oxysterol-dependent activation of PERK/ATF4 axis causing cell death

Yuichi Watanabe1,2, Takashi Sasaki1, Shoko Miyoshi1, Makoto Shimizu1, Yoshio Yamauchi1, Ryuichiro Sato1 (1.Dept. of Appl. Biol. Chem., Grad. Sch. of Agric. and Life Sci., Univ. of Tokyo, 2.Div. of Biol. Chem., Dept. of Pharm. Sci., Sch. of Pharm., Showa Univ.)

キーテクノロジー:CRISPR/Cas9

酸化ステロール、INSIG、細胞死、ATF4

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